Genus Solanum comprises 2000 species, nine of which are presents in flora of Serbia and Montenegro. The plants are known to produce steroidal glycoalkaloids. Due to their high toxicity the use of these plant species in folk and official medicine is limited. Although many data regarding to the alkaloids and related saponins in Solanum sp. are accessible, there is no available literature about the other natural products. In order to get more information about the taxonomic and chemical characteristic of Solanum species in Vojvodina, recently we started with the detail chemosystematic study of two Solanum species: Solanum nigrum L. and Solanum dulcamara L.

In the present study the total content and composition of phenolic compounds in the leaves of three populations of both S. nigrum and S. dulacmara from Vojvodina were examined. Phenolic compounds were separated by the successive preparative paper chromatography and identified by the spectroscopic methods. Phenolic acids and flavonoids were identified as main compounds. The obtained results showed that examined species clearly differed both in the content and composition of phenolic compounds and thus suggested that flavonoids and phenolic acid could be used in the chemosystematic study of these species.