The best mode of Hypericum crop establishment in lowland areas was investigated in South Banat region (Pančevo, Yugoslavia) during the period 1997-1999. Field experiments were carried out on humogley soil type. Mode of establishment was tested by sowing seed directly into the field and transplanting of seedlings in two periods, autumn and spring. Two types of yield were measured; flower (15 cm from the top of the plant), herb (25 cm from the top of the plant). Other facts important for knowledge of cultivation technology were observed too.

Method of direct sowing into the field failed in both term of sowing. Transplanting of seedlings was successful method for Hypericum crop establishment. Damage of freezing at Hypericum transplanted in autumn, varied 20-35% depending on time of planting, seedling quality and cold intensity during the winter. Missing plants were substituted in spring every year.

Plants transplanted in autumn were attained two cuts in first year and total yield was 2.0 t/ha (flower) or 3.1 t/ha herb, but the plants transplanted in spring were attained only one cut and yield was 0.45 t/ha flower or 0.75 t/ha herb. Plant development and attained yield in second year were similar in both time of transplanting. In the second year yield was 3.3-3.7 times more than in first year. In the first cut yield was 3.9 t/ha flower or 7.3 t/ha herb and in second cut 2.9 t/ha flower, while second cut of herb was lost because of plant disease.

Plant disease in form of withering, which spread over the sprouts and branch, in the beginning, and later on the whole plant, appeared in both experimental years. The withering in developed stage turns into necrosis and drying of leaves, branches and whole plant. Intensity of disease depends on the plant's age and climatic conditions. Cause of this disease is probably vascular fungus parasite, and intensive investigations are in progress.

Key words: Hypericum, cultivation, crop establishment, yield of flower, yield of herb.